Many people with allergies take antihistamines for relief. Studies show that several over-the-counter allergy medications are safe to use during pregnancy, including

  • chlorpheniramine

  • dexchlorpheniramine

  • hydroxyzine

Newer antihistamines, such as cetirizine and loratadine, also may be safe. There also is a corticosteroid nasal spray that is safe to use during pregnancy. But one of the most common decongestants, pseudoephedrine, has been linked to a small risk of abdominal wall birth defects. Do not use pseudoephedrine during the first 3 months of pregnancy.

Check with your ob-gyn before taking any over-the-counter allergy medication.

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Published: February 2021

Last reviewed: February 2021

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