Hormone Therapy: Resource Overview

Menopause occurs when a woman’s ovaries stop producing hormones, resulting in the end of her menstrual periods. To manage menopause symptoms, such as hot flashes and vaginal dryness, women may choose to begin hormone therapy.

Hormone therapy is medication that contains female hormones, either estrogen alone or estrogen and progestin together, to replace the ones the body is no longer making. There are risks and benefits to hormone therapy. Ob-gyns, physicians whose primary responsibility is women’s health, are best suited to help women determine if hormone therapy may be right for them.

Here are the key publications and resources for ob-gyns, other women’s health care providers, and patients from the American College of Obstetricians and Gynecologists (ACOG) and other sources.

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Resources for Ob-Gyns and Women’s Health Care Providers
Resources for Women and Patients

Resources for Ob-Gyns and Women’s Health Care Providers

Practice Bulletin: Management of Menopausal Symptoms (members only)

“Management of Menopausal Symptoms," issued by ACOG in January 2014 (reaffirmed 2016), addresses the treatment of menopausal symptoms, including hot flashes and vaginal atrophy, the thinning, drying, and inflammation of the vaginal walls. Hormone therapy, nonhormonal therapy, and other alternative treatments are reviewed.

Committee Opinion: Compounded Bioidentical Menopausal Hormone Therapy

“Compounded Bioidentical Menopausal Hormone Therapy,” issued by ACOG in August 2012 (reaffirmed 2016), discusses compounded bioidentical hormone therapy for menopause symptoms and gives recommendations for patient counseling. Compounding is the creation of an individualized medication for a specific patient, based on a physician’s prescription.

Committee Opinion: Hormone Therapy and Heart Disease

“Hormone Therapy and Heart Disease,” issued by ACOG in June 2013 (reaffirmed 2015), concludes that hormone therapy should not be used for prevention of heart disease. It also notes that hormone therapy does not increase heart disease risk for healthy women in early menopause and can be used for the relief of menopausal symptoms.

Committee Opinion: Postmenopausal Estrogen Therapy: Route of Administration and Risk of Venous Thromboembolism

“Postmenopausal Estrogen Therapy: Route of Administration and Risk of Venous Thromboembolism,” issued by ACOG in April 2013 (reaffirmed 2015), reviews the evidence on the safety of hormone therapy for menopause symptoms. This guideline notes that hormone therapy is associated with an increased risk of blood clots, called venous thromboembolism; however, the risk is low in healthy women without additional risk factors.

Practice Bulletin: Osteoporosis (members only)

“Osteoporosis,” issued by ACOG in September 2012 (reaffirmed 2016), reviews the prevention, screening, diagnosis, and treatment of osteoporosis. This evidence-based guideline recommends that ob-gyns address bone health with each of their patients, including lifestyle factors that may affect bone density and fracture risk. It includes updated recommendations for calcium and vitamin D levels for women.

Committee Opinion: Hormone Therapy in Primary Ovarian Insufficiency

"Hormone Therapy in Primary Ovarian Insufficiency," issued by ACOG in May 2017, discusses systemic hormone therapy as an approach to mitigating long-term health risks and treating the symptoms of hypoestrogenism in primary ovarian insufficiency.

Resources for Women and Patients

Patient FAQ: The Menopause Years

“The Menopause Years,” issued by ACOG in May 2015, was developed for patients who may have questions about menopause signs, symptoms, and treatments, including hormone therapy.

Patient Education Fact Sheet: Hormone Therapy

“Hormone Therapy,” issued by ACOG in April 2015 provides information for patients on hormone therapy treatment for managing menopause symptoms. Learn more about the different types of hormone therapy, the benefits and risks of hormone therapy, and alternative treatments for menopause symptoms.


The American College of Obstetricians and Gynecologists (ACOG), a 501(c)(3) organization, is the nation’s leading group of physicians providing health care for women. As a private, voluntary, nonprofit membership organization of more than 58,000 members, ACOG strongly advocates for quality women’s health care, maintains the highest standards of clinical practice and continuing education of its members, promotes patient education, and increases awareness among its members and the public of the changing issues facing women’s health care.


American College of Obstetricians and Gynecologists
409 12th Street SW, Washington, DC  20024-2188
Mailing Address: PO Box 96920, Washington, DC 20024-9998