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On December 7, 2017, a cohort study analyzing the risk of invasive breast cancer in women who used hormonal contraception was published in the New England Journal of Medicine. The study was designed to assess the influence of hormonal contraceptive use on the development of cardiovascular disease and cancer in a national cohort of Danish women.


Committee Opinion Number 729, January 2018

(Replaces Committee Opinion Number 493, May 2011)

ABSTRACT: Awareness of the broader contexts that influence health supports respectful, patient-centered care that incorporates lived experiences, optimizes health outcomes, improves communication, and can help reduce health and health care inequities. Although there is little doubt that genetics and lifestyle play an important role in shaping the overall health of individuals, interdisciplinary researchers have demonstrated how the conditions in the environment in which people are born, live, work, and age, play equally as important a role in shaping health outcomes. These factors, referred t...


Practice Bulletin Number 189, January 2018

(Replaces Practice Bulletin 153, September 2015)

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Committee Opinion Number 728, January 2018

(Replaces Committee Opinion Number 562, May 2013)

ABSTRACT: Müllerian agenesis, also referred to as müllerian aplasia, Mayer-Rokitansky-Küster-Hauser syndrome, or vaginal agenesis, has an incidence of 1 per 4,500–5,000 females. Müllerian agenesis is caused by embryologic underdevelopment of the müllerian duct, with resultant agenesis or atresia of the vagina, uterus, or both. Patients with müllerian agenesis usually are identified when they are evaluated for primary amenorrhea with otherwise typical growth and pubertal development. The most important steps in the effective management of müllerian agenesis are correct diagnosis of the underly...


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