Answers to the CME Quiz for “Screening and Follow-up of the Patient at High Risk for Breast Cancer” by Shawna C. Willey, MD, and Costanza Cocilovo, MD (Obstet Gynecol 2007;110:1404-16)

1. According to the authors, the Gail model should not be used to evaluate the risk of breast cancer for which of the following?

A. Women with a prior history of breast cancer

2. Which of the following historic factors or findings convey the greatest risk for breast cancer?

D. Therapeutic thoracic radiation before age 30

3. Tamoxifen chemoprevention for breast cancer is associated with a reduction in the incidence of breast cancer by a factor of approximately:

C. 2

4. A side effect of tamoxifen chemoprevention for breast cancer is:

E. A reduced risk of osteoporotic fractures

5. A patient with a history of both breast cancer and either a BRCA1 or BRCA2 mutation has a 10-year risk of cancer in the contralateral breast that approximates:

A. 35%

6. The authors state that the single most beneficial intervention for premenopausal gene mutation carriers to reduce the risk of both ovarian and breast cancer is:

D. Bilateral salpingoophorectomy

7. When compared to traditional mammography, magnetic resonance imaging (MRI) is characterized by:

B. Higher sensitivity and moderate specificity

8. American Cancer Society recommendations would suggest magnetic resonance imaging (MRI) screening in addition to traditional mammography for which of the following patients?

B. A patient with a BRCA1 gene mutation

ACCME Accreditation: The American College of Obstetricians and Gynecologists (ACOG) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. (Continuing medical education credit for “Screening and Follow-up of the Patient at High Risk for Breast Cancer” will be available through December 2010.)

AMA PRA Category 1 Credit^TM and ACOG Cognate Credit: The American College of Obstetricians and Gynecologists (ACOG) designates this educational activity for a maximum of 2 AMA PRA Category 1 Credits^TM or up to a maximum of 2 Category 1 ACOG cognate credits. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Disclosure Statement: Current guidelines state that continuing medical education (CME) providers must ensure that CME activities are free from the control of any commercial interest. All authors, reviewers, and contributors have disclosed to ACOG all relevant financial relationships with any commercial interests. The authors, reviewers, and contributors declare that neither they nor any business associate nor any member of their immediate families has financial interest or other relationships with any manufacturer of products or any providers of services discussed in this program. Any conflicts have been resolved through group and outside review of all content.

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