Noninvasive Prenatal Testing for Fetal Aneuploidy

Number 545

ABSTRACT: Noninvasive prenatal testing that uses cell free fetal DNA from the plasma of pregnant women offers tremendous potential as a screening tool for fetal aneuploidy. Cell free fetal DNA testin...

Reproductive Health Care for Incarcerated Women and Adolescent Females

Number 535

ABSTRACT: Increasing numbers of women and adolescent females are incarcerated each year in the United States and they represent an increasing proportion of inmates in the U.S. correctional system. In...

Lead Screening During Pregnancy and Lactation

Number 533

ABSTRACT: Prenatal lead exposure has known adverse effects on maternal health and infant outcomes across a wide range of maternal blood lead levels. Adverse effects of lead exposure are being identif...

Placenta Accreta

Number 529

ABSTRACT: Placenta accreta is a potentially life-threatening obstetric condition that requires a multidisciplinary approach to management. The incidence of placenta accreta has increased and seems to...

Intimate Partner Violence

Number 518

ABSTRACT: Intimate partner violence (IPV) is a significant yet preventable public health problem that affects millions of women regardless of age, economic status, race, religion, ethnicity, sexual o...

Screening and Diagnosis of Gestational Diabetes Mellitus

Number 504

Abstract: Gestational diabetes mellitus (GDM), defined as carbohydrate intolerance that begins or is first recognized during pregnancy, is associated with increased maternal, fetal, and neonatal risk...

At-Risk Drinking and Alcohol Dependence - Obstetric and Gynecologic Implications

Number 496

ABSTRACT: Compared with men, at-risk alcohol use by women has a disproportionate effect on their health and lives, including reproductive function and pregnancy outcomes. Obstetrician–gynecologists h...

Update on Carrier Screening for Cystic Fibrosis

Number 486

(Replaces No. 325, December 2005)

ABSTRACT: In 2001, the American College of Obstetricians and Gynecologists and the American College of Medical Genetics introduced guidelines for prenatal and preconception carrier screening for cyst...

Newborn Screening

Number 481

(Replaces No. 393, December 2007)

ABSTRACT: Newborn screening programs are mandatory, state-based public health programs. They provide newborns in the United States with presymptomatic testing and necessary follow-up care for a varie...

Carrier Screening for Fragile X Syndrome

Number 469

(Replaces No. 338, June 2006)

ABSTRACT: Fragile X syndrome is the most common inherited form of mental retardation. The syndrome occurs in approximately 1 in 3,600 males and 1 in 4,000–6,000 females. Approximately 1 in 250 female...

Screening for Depression During and After Pregnancy

Number 453

(Reaffirmed 2012)

Abstract: Depression is very common during pregnancy and the postpartum period. At this time, there is insufficient evidence to support a firm recommendation for universal antepartum or postpartum sc...

Array Comparative Genomic Hybridization in Prenatal Diagnosis

Number 446

ABSTRACT: The widespread use of array comparative genomic hybridization (CGH) for the diagnosis of genomic rearrangements in children with idiopathic mental retardation, developmental delay, and mult...

Preconception and Prenatal Carrier Screening for Genetic Diseases in Individuals of Eastern European Jewish Descent

Number 442

(Replaces No. 298, August 2004)

ABSTRACT: Certain autosomal recessive disease conditions are more prevalent in individuals of Eastern European Jewish (Ashkenazi) descent. Previously, the American College of Obstetricians and Gyneco...

Postpartum Screening for Abnormal Glucose Tolerance in Women Who Had Gestational Diabetes Mellitus

Number 435

ABSTRACT: Establishing the diagnosis of gestational diabetes mellitus offers an opportunity not only to improve pregnancy outcome, but also to decrease risk factors associated with the subsequent dev...

Human Immunodeficiency Virus

Number 389

ABSTRACT: Because human immunodeficiency virus (HIV) infection often is detected through prenatal and sexually transmitted disease testing, an obstetrician–gynecologist may be the first health profes...

Fetal Monitoring Prior to Scheduled Cesarean Delivery

Number 382

(Reaffirmed 2010)

ABSTRACT: There are insufficient data to determine the value of fetal monitoring prior to scheduled cesarean delivery in patients without risk factors.   With the increasing rate of schedule...

Umbilical Cord Blood Gas and Acid-Base Analysis

Number 348

(Reaffirmed 2012)

ABSTRACT: Umbilical cord blood gas and acid-base assessment are the most objective determinations of the fetal metabolic condition at the moment of birth. Moderate and severe newborn encephalopathy, ...

The Apgar Score

Number 333

(Reaffirmed 2010, Replaces No. 174, July 1996)

ABSTRACT: The Apgar score provides a convenient shorthand for reporting the status of the newborn infant and the response to resuscitation. The Apgar score has been used inappropriately to predict sp...

Inappropriate Use of the Terms Fetal Distress and Birth Asphyxia

Number 326

ABSTRACT: The Committee on Obstetric Practice is concerned about the continued use of the term "fetal distress" as an antepartum or intrapartum diagnosis and the term "birth asphyxia" as a neonatal d...

Screening for Tay - Sachs Disease

Number 318

(Reaffirmed 2010, Replaces No. 162, November 1995)

ABSTRACT: Tay–Sachs disease (TSD) is a severe progressive neurologic disease that causes death in early childhood. Carrier screening should be offered before pregnancy to individuals and couples at h...

Guidelines for Diagnostic Imaging During Pregnancy

Number 299

(Reaffirmed 2009, Replaces No. 158, September 1995)

ABSTRACT: Undergoing a single diagnostic X-ray procedure does not result in radiation exposure adequate to threaten the well-being of the developing preembryo, embryo, or fetus and is not an indicati...

Avoiding Inappropriate Clinical Decisions Based on False-Positive Human Chorionic Gonadotropin Test Results

Number 278

(Reaffirmed 2009)

ABSTRACT: Clinically significant false-positive human chorionic gonadotropin (hCG) test results are rare. However, some individuals have circulating factors in their serum (eg, heterophilic antibodie...