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Title Date
1.

Labor Induction or Augmentation and Autism

Number 597

Abstract Functional oxytocin deficiency and a faulty oxytocin signaling pathway have been observed in conjunction with autism spectrum disorder ASD Because exogenous synthetic oxytocin commonly is administered for labor induction and augmentation some have hypothesized that synthetic oxytocin used...

May 2014

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2.

Maternal–Fetal Surgery for Myelomeningocele

Number 550

ABSTRACT Myelomeningocele the most severe form of spina bifida occurs in approximately 1 in 1500 births in the United States Fetuses in whom myelomeningocele is diagnosed typically are delivered at term and are treated in the early neonatal period A recent randomized controlled trial found that fe...

January 2013

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3.

Noninvasive Prenatal Testing for Fetal Aneuploidy

Number 545

ABSTRACT Noninvasive prenatal testing that uses cell free fetal DNA from the plasma of pregnant women offers tremendous potential as a screening tool for fetal aneuploidy Cell free fetal DNA testing should be an informed patient choice after pretest counseling and should not be part of routine pre...

December 2012

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4.

Vitamin D: Screening and Supplementation During Pregnancy

Number 495

ABSTRACT During pregnancy severe maternal vitamin D deficiency has been associated with biochemical evidence of disordered skeletal homeostasis congenital rickets and fractures in the newborn At this time there is insufficient evidence to support a recommendation for screening all pregnant women f...

July 2011

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5.

Sulfonamides, Nitrofurantoin, and Risk of Birth Defects

Number 494

(Reaffirmed 2013)

Abstract The evidence regarding an association between the nitrofuran and sulfonamide classes of antibiotics and birth defects is mixed As with all patients antibiotics should be prescribed for pregnant women only for appropriate indications and for the shortest effective duration During the secon...

June 2011

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6.

Update on Carrier Screening for Cystic Fibrosis

Number 486

(Reaffirmed 2014, Replaces No. 325, December 2005)

ABSTRACT In 2001 the American College of Obstetricians and Gynecologists and the American College of Medical Genetics introduced guidelines for prenatal and preconception carrier screening for cystic fibrosis The American College of Obstetricians and Gynecologists Committee on Genetics has updated...

April 2011

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7.

Family History as a Risk Assessment Tool

Number 478

(Reaffirmed 2015)

ABSTRACT Family history plays a critical role in assessing the risk of inherited medical conditions and single gene disorders Several methods have been established to obtain family medical histories including the family history questionnaire or checklist and the pedigree The screening tool selecte...

March 2011

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8.

Carrier Screening for Fragile X Syndrome

Number 469

(Reaffirmed 2014, Replaces No. 338, June 2006)

ABSTRACT Fragile X syndrome is the most common inherited form of mental retardation The syndrome occurs in approximately 1 in 3600 males and 1 in 40006000 females Approximately 1 in 250 females carry the premutation DNAbased molecular analysis is the preferred method of diagnosis for fragile X syn...

October 2010

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9.

Moderate Caffeine Consumption During Pregnancy

Number 462

(Reaffirmed 2013)

ABSTRACT Moderate caffeine consumption less than 200 mg per day does not appear to be a major contributing factor in miscarriage or preterm birth The relationship of caffeine to growth restriction remains undetermined A final conclusion cannot be made at this time as to whether there is a correlat...

August 2010

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10.

Maternal Phenylketonuria

Number 449

(Replaces No. 230, January 2000)

ABSTRACT Phenylketonuria PKU is an autosomal recessive disorder of phenylalanine Phe metabolism characterized by a deficiency of the hepatic enzyme phenylalanine hydroxylase an enzyme responsible for the conversion of phenylalanine to tyrosine and elevated levels of Phe and Phe metabolite All wome...

December 2009

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11.

Air Travel During Pregnancy

Number 443

(Reaffirmed 2014, Replaces No. 264, December 2001)

ABSTRACT In the absence of obstetric or medical complications pregnant women can observe the same precautions for air travel as the general population and can fly safely Pregnant women should be instructed to continuously use their seat belts while seated as should all air travelers Pregnant air t...

October 2009

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12.

Preconception and Prenatal Carrier Screening for Genetic Diseases in Individuals of Eastern European Jewish Descent

Number 442

(Reaffirmed 2014, Replaces No. 298, August 2004)

ABSTRACT Certain autosomal recessive disease conditions are more prevalent in individuals of Eastern European Jewish Ashkenazi descent Previously the American College of Obstetricians and Gynecologists recommended that individuals of Eastern European Jewish ancestry be offered carrier screening fo...

October 2009

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13.

Guidelines for Diagnostic Imaging During Pregnancy

Number 299

(Replaces No. 158, September 1995, Reaffirmed 2014 )

ABSTRACT Undergoing a single diagnostic Xray procedure does not result in radiation exposure adequate to threaten the wellbeing of the developing preembryo embryo or fetus and is not an indication for therapeutic abortion When multiple diagnostic Xrays are anticipated during pregnancy imaging proc...

September 2004

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14.

Avoiding Inappropriate Clinical Decisions Based on False-Positive Human Chorionic Gonadotropin Test Results

Number 278

(Reaffirmed 2013)

ABSTRACT Clinically significant falsepositive human chorionic gonadotropin hCG test results are rare However some individuals have circulating factors in their serum eg heterophilic antibodies or nonactive forms of hCG that interact with the hCG antibody and cause unusual or unexpected test result...

November 2002

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15.

Management of Asymptomatic Pregnant or Lactating Women Exposed to Anthrax

Number 268

ABSTRACT Anthrax infections are diagnosed by isolating Bacillus anthracis from body fluids or by measuring specific antibodies in the blood of persons suspected to have the disease It is recommended that asymptomatic pregnant and lactating women who have been exposed to a confirmed environmental c...

February 2002

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American Congress of Obstetricians and Gynecologists
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