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1.

Microarrays and Next-Generation Sequencing Technology: The Use of Advanced Genetic Diagnostic Tools in Obstetrics and Gynecology

Committee Opinion Number 682, December 2016

(Replaces Committee Opinion Number 581, December 2013)

ABSTRACT Genetic technology has advanced dramatically in the past few decades and its applications and use in caring for and counseling pregnant women has been transformational in the realm of prenatal diagnosis Two of the newer genetic technologies in the prenatal setting are chromosomal microarr...

December 2016

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2.

Comprehensive Sexuality Education

Committee Opinion Number 678, November 2016

ABSTRACT Current sexuality education programs vary widely in the accuracy of content emphasis and effectiveness Data have shown that not all programs are equally effective for all ages races and ethnicities socioeconomic groups and geographic areas Studies have demonstrated that comprehensive sexu...

November 2016

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3.

Identification and Referral of Maternal Genetic Conditions in Pregnancy

Committee Opinion Number 643, October 2015

ABSTRACT Advances in the understanding of genetic conditions reproductive technologies and improved medical and surgical care have enabled an increasing number of women with genetic conditions to achieve a normal pregnancy outcome However management of certain genetic conditions during pregnancy i...

October 2015

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4.

Cell-free DNA Screening for Fetal Aneuploidy

Committee Opinion Number 640, September 2015

(This Committee Opinion Replaces Committee Opinion Number 545)

ABSTRACT Noninvasive prenatal screening that uses cellfree DNA from the plasma of pregnant women offers tremendous potential as a screening method for fetal aneuploidy A number of laboratories have validated different techniques for the use of cellfree DNA as a screening test for fetal aneuploidy ...

September 2015

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5.

Management of Women With Phenylketonuria

Committee Opinion Number 636, June 2015

(Replaces Committee Opinion Number 449, December 2009)

ABSTRACT Phenylketonuria PKU is an autosomal recessive disorder of phenylalanine Phe metabolism characterized by deficient activity of the hepatic enzyme phenylalanine hydroxylase Increased blood Phe levels are toxic to a variety of tissues particularly the developing fetal brain The mainstay of t...

June 2015

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6.

Family History as a Risk Assessment Tool

Committee Opinion Number 478, March 2011

(Reaffirmed 2015)

ABSTRACT Family history plays a critical role in assessing the risk of inherited medical conditions and single gene disorders Several methods have been established to obtain family medical histories including the family history questionnaire or checklist and the pedigree The screening tool selecte...

March 2011

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