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Title Date

Update on Carrier Screening for Cystic Fibrosis

Number 486

(Reaffirmed 2014, Replaces No. 325, December 2005)

ABSTRACT In 2001 the American College of Obstetricians and Gynecologists and the American College of Medical Genetics introduced guidelines for prenatal and preconception carrier screening for cystic fibrosis The American College of Obstetricians and Gynecologists Committee on Genetics has updated...

April 2011

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Carrier Screening for Fragile X Syndrome

Number 469

(Reaffirmed 2014, Replaces No. 338, June 2006)

ABSTRACT Fragile X syndrome is the most common inherited form of mental retardation The syndrome occurs in approximately 1 in 3600 males and 1 in 40006000 females Approximately 1 in 250 females carry the premutation DNAbased molecular analysis is the preferred method of diagnosis for fragile X syn...

October 2010

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Preconception and Prenatal Carrier Screening for Genetic Diseases in Individuals of Eastern European Jewish Descent

Number 442

(Reaffirmed 2014, Replaces No. 298, August 2004)

ABSTRACT Certain autosomal recessive disease conditions are more prevalent in individuals of Eastern European Jewish Ashkenazi descent Previously the American College of Obstetricians and Gynecologists recommended that individuals of Eastern European Jewish ancestry be offered carrier screening fo...

October 2009

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The Role of Transvaginal Ultrasonography in the Evaluation of Postmenopausal Bleeding

Number 440

(Reaffirmed 2013)

ABSTRACT The clinical approach to postmenopausal bleeding requires prompt and efficient evaluation to exclude or diagnose carcinoma Women with postmenopausal bleeding may be assessed initially with either endometrial biopsy or transvaginal ultrasonography this initial evaluation does not require p...

August 2009

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Preimplantation Genetic Screening for Aneuploidy

Number 430

(Reaffirmed 2014)

ABSTRACT Preimplantation genetic screening differs from preimplantation genetic diagnosis for single gene disorders and was introduced for the detection of chromosomal aneuploidy Current data does not support a recommendation for preimplantation genetic screening for aneuploidy using fluorescence ...

March 2009

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Human Immunodeficiency Virus

Number 389

ABSTRACT Because human immunodeficiency virus HIV infection often is detected through prenatal and sexually transmitted disease testing an obstetriciangynecologist may be the first health professional to provide care for a woman infected with HIV Universal testing with patient notification and rig...

December 2007

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Patient Testing Ethical Issues in Selection and Counseling

Number 363

(Reaffirmed 2012)

ABSTRACT Recommendations to patients about testing should be based on current medical knowledge a concern for the patients best interests and mutual consultation In addition to establishing a diagnosis testing provides opportunities to educate inform and advise The ethical principles of respect fo...

April 2007

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The Apgar Score

Number 333

(Reaffirmed 2010, Replaces No. 174, July 1996)

ABSTRACT The Apgar score provides a convenient shorthand for reporting the status of the newborn infant and the response to resuscitation The Apgar score has been used inappropriately to predict specific neurologic outcome in the term infant There are no consistent data on the significance of the ...

May 2006

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Screening for Tay - Sachs Disease

Number 318

(Reaffirmed 2014, Replaces No. 162, November 1995)

ABSTRACT TaySachs disease TSD is a severe progressive neurologic disease that causes death in early childhood Carrier screening should be offered before pregnancy to individuals and couples at high risk including those of Ashkenazi Jewish FrenchCanadian or Cajun descent and those with a family his...

October 2005

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Guidelines for Diagnostic Imaging During Pregnancy

Number 299

(Replaces No. 158, September 1995, Reaffirmed 2014 )

ABSTRACT Undergoing a single diagnostic Xray procedure does not result in radiation exposure adequate to threaten the wellbeing of the developing preembryo embryo or fetus and is not an indication for therapeutic abortion When multiple diagnostic Xrays are anticipated during pregnancy imaging proc...

September 2004

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Avoiding Inappropriate Clinical Decisions Based on False-Positive Human Chorionic Gonadotropin Test Results

Number 278

(Reaffirmed 2013)

ABSTRACT Clinically significant falsepositive human chorionic gonadotropin hCG test results are rare However some individuals have circulating factors in their serum eg heterophilic antibodies or nonactive forms of hCG that interact with the hCG antibody and cause unusual or unexpected test result...

November 2002

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American Congress of Obstetricians and Gynecologists
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