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Title Date
1.

Avoiding Inappropriate Clinical Decisions Based on False-Positive Human Chorionic Gonadotropin Test Results

Number 278

(Reaffirmed 2015)

ABSTRACT Clinically significant falsepositive human chorionic gonadotropin hCG test results are rare However some individuals have circulating factors in their serum eg heterophilic antibodies or nonactive forms of hCG that interact with the hCG antibody and cause unusual or unexpected test result...

November 2002

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2.

Guidelines for Diagnostic Imaging During Pregnancy

Number 299

(Replaces No. 158, September 1995, Reaffirmed 2014 )

ABSTRACT Undergoing a single diagnostic Xray procedure does not result in radiation exposure adequate to threaten the wellbeing of the developing preembryo embryo or fetus and is not an indication for therapeutic abortion When multiple diagnostic Xrays are anticipated during pregnancy imaging proc...

September 2004

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3.

Preimplantation Genetic Screening for Aneuploidy

Number 430

(Reaffirmed 2014)

ABSTRACT Preimplantation genetic screening differs from preimplantation genetic diagnosis for single gene disorders and was introduced for the detection of chromosomal aneuploidy Current data does not support a recommendation for preimplantation genetic screening for aneuploidy using fluorescence ...

March 2009

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4.

Preconception and Prenatal Carrier Screening for Genetic Diseases in Individuals of Eastern European Jewish Descent

Number 442

(Reaffirmed 2014, Replaces No. 298, August 2004)

ABSTRACT Certain autosomal recessive disease conditions are more prevalent in individuals of Eastern European Jewish Ashkenazi descent Previously the American College of Obstetricians and Gynecologists recommended that individuals of Eastern European Jewish ancestry be offered carrier screening fo...

October 2009

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5.

Carrier Screening for Fragile X Syndrome

Number 469

(Reaffirmed 2014, Replaces No. 338, June 2006)

ABSTRACT Fragile X syndrome is the most common inherited form of mental retardation The syndrome occurs in approximately 1 in 3600 males and 1 in 40006000 females Approximately 1 in 250 females carry the premutation DNAbased molecular analysis is the preferred method of diagnosis for fragile X syn...

October 2010

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6.

Update on Carrier Screening for Cystic Fibrosis

Number 486

(Reaffirmed 2014, Replaces No. 325, December 2005)

ABSTRACT In 2001 the American College of Obstetricians and Gynecologists and the American College of Medical Genetics introduced guidelines for prenatal and preconception carrier screening for cystic fibrosis The American College of Obstetricians and Gynecologists Committee on Genetics has updated...

April 2011

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7.

Noninvasive Prenatal Testing for Fetal Aneuploidy

Number 545

ABSTRACT Noninvasive prenatal testing that uses cell free fetal DNA from the plasma of pregnant women offers tremendous potential as a screening tool for fetal aneuploidy Cell free fetal DNA testing should be an informed patient choice after pretest counseling and should not be part of routine pre...

December 2012

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8.

Cell-free DNA Screening for Fetal Aneuploidy

Number 640

(Published Electronically Ahead of Print on June 26, 2015)
(This Committee Opinion Replaces Committee Opinion Number 545)

ABSTRACT Noninvasive prenatal screening that uses cellfree DNA from the plasma of pregnant women offers tremendous potential as a screening method for fetal aneuploidy A number of laboratories have validated different techniques for the use of cellfree DNA as a screening test for fetal aneuploidy ...

September 2015

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American Congress of Obstetricians and Gynecologists
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