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Identification and Referral of Maternal Genetic Conditions in Pregnancy

Committee Opinion Number 643, October 2015

ABSTRACT Advances in the understanding of genetic conditions reproductive technologies and improved medical and surgical care have enabled an increasing number of women with genetic conditions to achieve a normal pregnancy outcome However management of certain genetic conditions during pregnancy i...

October 2015

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Hereditary Cancer Syndromes and Risk Assessment

Committee Opinion Number 634, June 2015

ABSTRACT A hereditary cancer syndrome is a genetic predisposition to certain types of cancer often with onset at an early age caused by inherited mutations in one or more genes Cases of cancer commonly encountered by obstetriciangynecologists or other obstetricgynecologic providersmdashsuch as bre...

June 2015

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Newborn Screening and the Role of the Obstetrician-Gynecologist

Committee Opinion Number 616, January 2015

(Replaces Committee Opinion Number 481, March 2011)

ABSTRACT Newborn screening is a mandatory statebased public health program that provides all newborns in the United States with presymptomatic testing and necessary followup health care for a variety of medical conditions The goal of this essential public health program is to decrease morbidity an...

January 2015

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Von Willebrand Disease in Women

Committee Opinion Number 580, December 2013

(Replaces No. 451, December 2009, Reaffirmed 2015)

ABSTRACT Von Willebrand disease the most common inherited bleeding disorder among American women is a common cause of heavy menstrual bleeding and other bleeding problems in women and adolescent girls Von Willebrand disease and other inherited and acquired disorders of coagulation and hemostasis s...

December 2013

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Personalized Genomic Testing for Disease Risk

Committee Opinion Number 527, June 2012

(Reaffirmed 2016)

ABSTRACT Advances in genetic technologies have led to the identification of hundreds of single nucleotide polymorphisms that are associated with a variety of complex diseases including cancer diabetes cardiovascular disease and Alzheimer disease Although personalized genomic tests that provide inf...

June 2012

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Family History as a Risk Assessment Tool

Committee Opinion Number 478, March 2011

(Reaffirmed 2015)

ABSTRACT Family history plays a critical role in assessing the risk of inherited medical conditions and single gene disorders Several methods have been established to obtain family medical histories including the family history questionnaire or checklist and the pedigree The screening tool selecte...

March 2011

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Ethical Issues in Genetic Testing

Committee Opinion Number 410, June 2008

(Reaffirmed 2014)

ABSTRACT Genetic testing is poised to play an increasing role in the practice of obstetrics and gynecology To assure patients of the highest quality of care physicians should become familiar with the currently available array of genetic tests and the tests limitations Clinicians should be able to ...

June 2008

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Direct-to-Consumer Marketing of Genetic Testing

Committee Opinion Number 409, June 2008

Reaffirmed 2016

ABSTRACT Marketing of genetic testing although similar to directtoconsumer advertising of prescription drugs raises additional concerns and considerations These include issues of limited knowledge among patients and health care providers of available genetic tests difficulty in interpretation of g...

June 2008

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