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Title Date

Screening for Perinatal Depression

Number 630

(Replaces Committee Opinion Number 453, February 2010)

ABSTRACT Perinatal depression which includes major and minor depressive episodes that occur during pregnancy or in the first 12 months after delivery is one of the most common medical complications during pregnancy and the postpartum period affecting one in seven women It is important to identify ...

May 2015

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Prenatal and Perinatal Human Immunodeficiency Virus Testing - Expanded Recommendations

Number 635

(Replaces Committee Opinion Number 418, September 2008)

ABSTRACT Given the enormous advances in the prevention of perinatal transmission of human immunodeficiency virus HIV it is clear that early identification and treatment of all pregnant women with HIV is the best way to prevent neonatal infection and also improve womens health Furthermore new evide...

June 2015

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Management of Women With Phenylketonuria

Number 636

(Replaces Committee Opinion Number 449, December 2009)

ABSTRACT Phenylketonuria PKU is an autosomal recessive disorder of phenylalanine Phe metabolism characterized by deficient activity of the hepatic enzyme phenylalanine hydroxylase Increased blood Phe levels are toxic to a variety of tissues particularly the developing fetal brain The mainstay of t...

June 2015

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Marijuana Use During Pregnancy and Lactation

Number 637

ABSTRACT Cannabis sativa marijuana is the illicit drug most commonly used during pregnancy The selfreported prevalence of marijuana use during pregnancy ranges from 2 to 5 in most studies A growing number of states are legalizing marijuana for medicinal or recreational purposes and its use by preg...

July 2015

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First-Trimester Risk Assessment for Early-Onset Preeclampsia

Number 638

ABSTRACT Hypertensive disorders with adverse sequelae including preterm birth maternal morbidity and mortality and longterm risk of maternal cardiovascular disease complicate 510 of pregnancies Early identification of pregnant women at risk of developing earlyonset preeclampsia would theoretically...

September 2015

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Cell-free DNA Screening for Fetal Aneuploidy

Number 640

(This Committee Opinion Replaces Committee Opinion Number 545)

ABSTRACT Noninvasive prenatal screening that uses cellfree DNA from the plasma of pregnant women offers tremendous potential as a screening method for fetal aneuploidy A number of laboratories have validated different techniques for the use of cellfree DNA as a screening test for fetal aneuploidy ...

September 2015

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Identification and Referral of Maternal Genetic Conditions in Pregnancy

Number 643

ABSTRACT Advances in the understanding of genetic conditions reproductive technologies and improved medical and surgical care have enabled an increasing number of women with genetic conditions to achieve a normal pregnancy outcome However management of certain genetic conditions during pregnancy i...

October 2015

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