Zika virus is a mosquito-transmitted virus that generally causes no symptoms or mild illness, but is associated with microcephaly in infants whose mothers contract it during pregnancy. In January 2016, the US Centers for Disease Control and Prevention (CDC) issued a health advisory, travel alert and MMWR urging women who are pregnant to avoid countries where Zika virus transmission is ongoing. Women trying to become pregnant should consult with their healthcare providers before traveling to these areas and strictly follow steps to avoid mosquito bites during the trip. Information on this webpage, including recommendations for management, will be updated periodically to reflect changing evidence and emerging consensus.
ACOG Practice Advisory
The ACOG-SMFM Practice Advisory: Updated Interim Guidance for Care of Women of Reproductive Age During a Zika Virus Outbreak has been modified to include CDC's update on submitting urine samples with blood samples for PCR testing. June 13, 2016
ACOG Zika Virus Email Blast Updates
Updated Recommendations on rRT-PCR and IgM Testing June 23, 2016
Interpretation of Zika Virus Antibody Test Results June 13, 2016
Zika Testing on Urine and US Zika Pregnancy Registry May 27, 2016
ACOG Statements Regarding Zika Virus
ACOG Statement on Zika Virus Transmission, July 18, 2016. Please refer to the MMWR Preventing Transmission of Zika Virus in Labor and Delivery Settings Through
Implementation of Standard Precautions — United States, 2016.
ACOG Statement on Congress’ Failure to Take Action on Zika, July 14, 2016
A Message to the US Congress from ACOG President Thomas Gellhaus, MD on the Zika Virus Conference Report, June 23, 2016
ACOG Statement on New England Journal of Medicine Study on Zika and Abortion Requests, June 22, 2016
ACOG Statement on the CDC Update on Zika Virus, April 13, 2016
ACOG LARC Program
Visit ACOG's The LARC Program webpage as a resource for LARC-related information regarding Zika Virus.
ACOG Annual Clinical and Scientific Meeting
Late Breaking Lecture – The Latest on the Zika Virus: Ob/Gyn Response in This World of Uncertainty Laura E. Riley, MD and Denise Jamieson, MD presented on Sunday, May 15, 2016
Click here to watch the late-breaking presentation on Zika Virus (ACOG members only) This session presented an overview of what is known about Zika virus with particular attention paid to pregnancy implications. This lecture also reviewed what is not known about the pathogenesis of the virus. In this time of uncertainty, guidance on prevention, screening, and treatment will be discussed as well.
CDC Zika Pregnancy Hotline for Healthcare Providers
Ob-gyns can contact the CDC Zika Pregnancy Hotline at 770-488-7100 or email ZikaPregnancy@cdc.gov for any concerns related to clinical management or the US Zika Pregnancy Registry
Diagnostic Testing on CDC.gov
Zika virus disease can often be diagnosed by performing reverse transcriptase-polymerase chain reaction (RT-PCR) on serum. Testing is performed at the CDC Arbovirus Diagnostic Laboratory and a few state health departments.
Contact your state health department for local direction on handling specimens for testing. To find your state contact refer to the Zika state contact list from CDC (members-only PDF).
Zika Testing on Urine
On May 13, 2016, the Centers for Disease Control and Prevention (CDC) issued interim guidance that recommends Zika virus rRT-PCR testing of urine collected less than 14 days after symptom onset, along with testing of patient-matched serum samples, for the diagnosis of suspected Zika infection. If the PCR result is negative, serologic (IgM) testing should be performed. CDC recommendations for Zika virus testing of serum and other clinical specimens remain unchanged at this time. Learn more.
US Zika Pregnancy Registry
To better facilitate reporting, the CDC has provided a contact list (ACOG members only) of US Zika Pregnancy Registry contacts for each state.
CDC Reporting Data: Pregnant Women with Any Lab Evidence of Zika Virus Infection
Click Here For Cases in Pregnancy
Click here For Pregnancy Outcomes
CDC fact sheets and checklists on US Zika Pregnancy Registry for obstetric healthcare providers, Doctor's visit Checklist for Healthcare Providers and pregnant women.
Zika Virus Response Planning: Interim Guidance for District and School Administrators in the Continental United States and Hawaii
CDC Communication Toolkit – US Zika Pregnancy Registry Adverse Outcomes reporting
ISUOG Congenital Zika Virus Syndrome: how to improve your diagnostic capabilities
As pregnant women and their fetuses are being diagnosed with Congenital Zika Virus Syndrome with increased frequency in Brazil as well as in other Latin American countries, it becomes crucial to educate regional practitioners on the way to make these diagnoses as early as possible. ISUOG Outreach has organized, in collaboration with the World Health Organization (WHO). a free webinar on the subject to provide participants with the necessary tools to differentiate between unaffected and affected fetuses.
Click Here to watch webinar on demand