Ages 40-64 Years: Laboratory and Other Tests

Jump to:
Ages 40-64 Years
     Evaluation and counseling


□ Cervical cytology: Preferred--Co-test with cytology and HPV testing every 5 years;  Option--Screen with cytology alone every 3 years
□ Colorectal cancer screening: Preferred--beginning at age 50 years: colonoscopy every 10 years*

Test That Detects
Adenomatous Polyps
and Cancer
Colonoscopy (preferred) Every 10 years
Flexible sigmoidoscopy with insertion to 40 cm or to splenic flexure Every 5 years
CTC Every 5 years
gFOBT with high sensitivity for cancer Annual
FIT with high sensitivity for cancer Annual
sDNA with high sensitivity Interval uncertain

□ Diabetes testing -beginning at age 45 years (If tests are normal, repeat testing carried out at a minimum of 3-year intervals is reasonable.)

□ Genetic testing/counseling (screening for spinal muscular atrophy, cystic fibrosis carrier, and assessment for risk of a hemoglobinopathy should be offered to all women who are considering pregnancy)

□Hepatitis C virus testing -one-time testing for persons born from 1945 through 1965 and unaware of their infection status
□ Human immunodeficiency virus (HIV) testing - Physicians should be aware of and follow  their states' HIV screening requirements. Visit the Centers for Disease Control and Prevention for more information.
□ Lipid profile assessment - every 5 years beginning at age 45 years
□ Mammography - yearly

High-Risk Groups (See High-Risk Table for more information.)

□ Bone mineral density screening
□ Colorectal cancer screening
□ Diabetes testing

□ Genetic testing/counseling (fragile X syndrome, Tay–Sachs disease) 

□ Hemoglobin level assessment
□ Lipid profile assessment
□ Sexually transmitted infection testing
□ Thyroid-stimulating hormone testing
□ Tuberculosis skin testing

*Colorectal cancer screening for African American women should begin at age 45 years.

American Congress of Obstetricians and Gynecologists
409 12th Street SW, Washington, DC  20024-2188 | Mailing Address: PO Box 70620, Washington, DC 20024-9998